Pharmacokinetics
It is a fundamental aspect of drug discovery and development, focusing on how a drug behaves inside a living organism. These studies provide real-world data on absorption, distribution, metabolism, and excretion (ADME), helping researchers understand the drug’s fate and optimize its therapeutic potential.
Dose Linearity – Single / Multiple dose
Species
- CD-1 mouse
- Sprague Dawley Rats
- Wistar Rats
- Beagle Dogs
Dose Proportionality
Species
- CD-1 mouse
- Sprague Dawley Rats
- Wistar Rats
- Beagle Dogs
Bioavailability and Bioequivalence
Species
- CD-1 mouse
- Sprague Dawley Rats
- Wistar Rats
- Beagle Dogs
Discrete / Cassette
Species
- CD-1 mouse
- Sprague Dawley Rats
- Wistar Rats
Parallel / Crossover
Species
- Beagle Dogs
Effect of Food and Gender
Species
- CD-1 mouse
- Sprague Dawley Rats
- Wistar Rats
- Beagle Dogs
Disposition Studies in Rats using bile duct cannulation
Species
- Sprague Dawley Rats
- Wistar Rats
Tissue Distribution (Non-radioactive)
Species
- CD-1 mouse
- Sprague Dawley Rats
- Wistar Rats
Brain Penetration
Species
- CD-1 mouse
- Sprague Dawley Rats
- Wistar Rats
Ocular PK
Dermal PK
Species
- CD-1 mouse
- Sprague Dawley Rats
- Wistar Rats
Noncompartmental and Compartmental Method using Phoenix Win-Nonlin
–
Solution
- IV dosing
Suspension
- Per oral dosing
Channel partners
Non-GLP studies
GVRP
Species
- CD-1 mouse
- C57BL6 mouse
- Balb/c mouse
- Nude mouse
- Sprague Dawley Rats
- Wistar Rats
Palamur Biosciences
Species
- CD-1 mouse
- C57BL6 mouse
- Balb/c mouse
- Nude mouse
- Sprague Dawley Rats
- Wistar Rats
- Beagle Dogs
Biolivz Research Center
Species
- CD-1 mouse
- C57BL6 mouse
- Balb/c mouse
- Sprague Dawley Rats
- Wistar Rats
GLP Studies
Palamur Biosciences
Species
- CD-1 mouse
- Sprague Dawley Rats
- Wistar Rats
- Beagle Dogs
- Rhesus Monkeys
Pharmaron
Species
- Rhesus Monkeys
- Cyno Monkeys
End point data analytics
Palamur Biosciences
Species
- Rodent: Mice, Rat and Guinea Pig
- Non-Rodent: Beagle Dog, Rabbit
Preclinical formulation preparation and screening
Is a vital step in drug discovery and development, aimed at identifying suitable formulations for in vivo studies. It ensures that drug candidates are delivered in a form that maximizes bioavailability, stability, and safety, while also being compatible with the intended route of administration.
